Healthy elderly subjects
Conditions
Interventions
24 weeks ingestion of active food
24 weeks ingestion of placebo food
Sponsors
Meiji Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subjects giving written informed consent 2) Participants in the project for prevention of long-term frailty in Obihiro City, Hokkaido 3) Subjects aged 65 to 85 years old when consent acquisition 4) Subjects whose MMSE score is 22 points or more
Exclusion criteria
Exclusion criteria: 1) Subjects who have diagnosed with dementia, malignant tumor, chronic renal failure or diabetes 2) Subjects who have significant abnormal blood test score 3) Subjects who are prescribed antipsychotics, dementia treatment drugs, ethyl icosapentaebiate or omega 3-fatty acid ethyl 4) Subjects taking supplements that are expected to improve brain function more than 4 days a week 5) Subjects taking supplements containing EPA and/or DHA more than 4 days a week 6) Subjects who are prescribed anticoagulants and antiplatelet drugs. 7) Subjects who have milk allergy or lactose intolerance 8) Subjects who have soy allergy 9) Subjects who participate in other clinical trials within the past month or have plans to participate in other clinical trials during this study period 10)Subjects who determine ineligible by the principal investigator or sub-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE, MoCA, Plasma BDNF concentration, Plasma NGF concentration, Plasma omega 3-fatty acids concentration (DHA and EPA), Plasma DHA concentration, Plasma EPA concentration, CRP concentration, Lean body mass, BMI, SMI, Subjective health status, Frequency of going out | — |
Countries
Japan
Contacts
Public ContactYoshimura Aya
Meiji Co., Ltd. R&D Division
Outcome results
None listed