Healthy adult
Conditions
Interventions
Amino acids(4 g, once a day, for 2 weeks)
Placebo(4 g, once a day, for 2 weeks)
Sponsors
KSO corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female aged 20 or higher and less than 60 years old. 2. Individuals who have discomfort in Achilles tendon and do not show blood vessel infiltration into Achilles tendon evaluated by an ultrasonography. 3. Individuals who have discomfort in Achilles tendon during exercise or the day after exercise 4. Individuals who exercise more than 2 times a week. 5. Individuals who can make self-judgment and voluntarily provides written informed consent.
Exclusion criteria
Exclusion criteria: 1. Individuals who had a surgery or local injections within one year. 2. Individuals who are in need of a treatment for Achilles tendon, judged by the principal investigator. 3. Individuals who have received a surgery for Achilles tendon in the past. 4. Individuals who are under medications which may affect Achilles tendon such as poultice, ointment or painkiller. 5. Individuals who have severe chronic diseases (hepatic, cardiovascular, respiratory, endocrine, and metabolic disorders) 6. Individuals who are impossible to stop taking supplements or functional foods which may affect Achilles tendon during this study. 7. Indivicuals who take amino acid -related medicines such as LIVACT, AminolebanEN and Hepan ED. 8. Individuals who regularly take amino acid/protein supplements. 9. Individuals who have amino acid metabolism disorders. 10. Individuals who are pregnant, lactating or have these plans. 11. Individuals who received more than 200 mL of blood collection within 12 weeks from the screening test. 12. Individuals who have participated in a study using other food intake or medicines, and cosmetics within one month retrospectively from the time of obtaining consent, or who are participating in other examinations during this study participation. 13. Individuals who are judged as unsuitable for the study by the investigator for the other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-alpha | — |
Countries
Japan
Contacts
Public ContactYoshika Komori
KSO Corporation Sales Department
Outcome results
None listed