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A clinical research to analyze mucosal permeability of endoscopic biopsy specimens by Ussing chamber experiment

Single-center, prospective, interventional clinical research to analyze mucosal permeability of endoscopic biopsy specimens by Ussing chamber experiment - Single-center, prospective, interventional clinical research to analyze mucosal permeability of endoscopic biopsy specimens by Ussing chamber experiment

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000044382
Enrollment
60
Registered
2021-05-31
Start date
2021-05-31
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases related to Increased mucosal permeability

Interventions

None listed

Sponsors

Chiba university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing gastrointestinal endoscopy at Chiba University Hospital. 2. Age 16 years or older. 3) Patients who have received sufficient explanation and understanding of the study and have given their free written consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Pregnancy. 2. Patients who have platelet and coagulation factor dysfunction and are considered to be at high risk of bleeding from mucosal biopsy. 3. Patients who are taking two or more antithrombotic agents or warfarin whose PT-INR is prolonged beyond the therapeutic range. 4. Patients who are deemed ineligible for participation in the study by the investigators and sub-investigators.

Design outcomes

Primary

MeasureTime frame
It is the short-circuit current value of the mucosal biopsy specimen using the Ussing chamber experiment.

Secondary

MeasureTime frame
Analyze the relationship between disease activity and prognosis (response to treatment), treatment details, and pathological evaluation and short circuit current values.

Countries

Japan

Contacts

Public Contactwataru shiratori

Chiba university gastroenterology

shiratori.wataru@chiba-u.jp08066531290

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026