Elucidation of the pathophysiology of artificial valve dysfunction after bioprosthetic valve replacement

Elucidation of the pathophysiology of artificial valve dysfunction after bioprosthetic valve replacement - Elucidation of the pathophysiology of artificial valve dysfunction after bioprosthetic valve replacement

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044349

Enrollment

Registered

2021-06-01

Start date

2021-08-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

structural valve deterioration after bioprosthetic valve replacement

Interventions

18F-NaF PET will be performed for patients after bioprosthetic valve replacement at our institute who have given informed consent. Standardized uptake value (SUV) max/mean of 18F on bioprosthetic valv

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who have undergone bioprosthetic valve replacement at our institutel and are following up

Exclusion criteria

Exclusion criteria: Age under 20 years old, cancer-bearing patients

Design outcomes

Primary

Measure	Time frame
To assess whether there a correlation between the occurrence of svd after artificial valve replacement and the result of PET examination or not	—

Secondary

Measure	Time frame
To assess what patients are more likely to have SVD and whether there are differences in the type of valves used	—

Countries

Japan

Contacts

Public ContactAi Kawamura

Osaka University Graduate School of Medicine Cardiovascular Surgery

a-shibamoto@surg1.med.osaka-u.ac.jp06-6879-3154

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026