Effect of intake of heat-killed lactic acid bacteria on the oral function.

Effect of intake of heat-killed lactic acid bacteria on the oral function. - Effect of intake of heat-killed LAB on the oral function.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044335

Enrollment

Registered

2023-05-30

Start date

2021-05-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of heat-killed LAB (high dose) for 6 weeks Ingestion of heat-killed LAB (low dose) for 6 weeks Ingestion of placebo for 6 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A health parson without a illness

Exclusion criteria

Exclusion criteria: 1.Persons with severe periodontal disease 2.Persons who take drugs for adiposity, hypertension and dyslipidemia 3.Persons who cannot give up the intake of possible supplements which may affect the status of fat, blood pressure and plasma lipids 4.Persons who cannot terminate the consumption of foods containing large number of lactic acid bacteria during the trial

Design outcomes

Primary

Measure	Time frame
Bleeding on probing, Gingival index, Probing pocket depth, Plaque index, Preriodontpathic bacteria, Tanque coating, Halitosis	—

Secondary

Measure	Time frame
Salivary flow	—

Countries

Japan

Contacts

Public ContactYoshimichi kozai

Kyowa Trial Co., Ltd. Clinical Trials Division

y-kohzai@kyowa-t.com08018692585

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026