Analgesic effects of lidocaine ropivacaine mixture for extraction of impacted mandibular third molar: a randomized controlled trial

Analgesic effects of lidocaine ropivacaine mixture for extraction of impacted mandibular third molar: a randomized controlled trial - Analgesic effects of lidocaine ropivacaine mixture for extraction of impacted mandibular third molar

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000044315

Enrollment

Registered

2021-06-01

Start date

2021-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impacted mandibular third molar

Interventions

anesthesia with lidocaine anesthesia with a mixture of lidocaine and ropivacaine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Outpatient undergoing extraction of mandibular implanted wisdom tooth

Exclusion criteria

Exclusion criteria: history of hypersensitivity to anesthetics, paresthesia in the area of innervation of the mandibular nerve, active infection or abscess in the oral and maxillofacial region, bleeding diathesis, use of anticoagulant or antiplatelet medications, and other medical history that might have affected the clinical trial (eg, uncontrolled hypertension or diabetes mellitus, heart failure, hyperthyroidism, psychiatric disorders)

Design outcomes

Primary

Measure	Time frame
Time from anesthesia to awareness of lower lip paresthesia	—

Secondary

Measure	Time frame
Success rates, time from anesthesia to awareness of post-extraction pain, time to first analgesic use after extraction, NRS after extraction, complications after extraction	—

Countries

Japan

Contacts

Public ContactTomoharu Hemmi

Okitama Public General Hospital dentistry, oral surgery

henmi@med.id.yamagata-u.ac.jp0238465000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026