All diseases that require surgery under general anesthesia
Conditions
Interventions
Induce anesthesia using Remimazolam.
Induce anesthesia using Propofol.
Sponsors
Kindai University Faculty of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients undergoing general anesthesia, regardless of gender. 2) Patients scheduled to undergo mechanical ventilation management by tracheal intubation 3) Patients with ASA classification I or II 4) Patients who can fully explain the complications, indications, and disadvantages associated with inferior alveolar nerve conduction anesthesia using detailed explanatory documents, and obtain written consent (informed consent) at their own will.
Exclusion criteria
Exclusion criteria: 1) Patients under the age of 20 at the time of obtaining the consent form 2) Patients with allergies, hypersensitivity or tolerance to the drugs used 3) Patients who meet the contraindications listed in the package insert of the drug to be used 4) Patients with AST (GOT) or ALT (GPT) of 100 IU / L or more in preoperative general clinical examination 5) Patients with Child-Pugh classification B or C 6) Patients with serum creatinine of 2.0 mg / dL or higher in general preoperative laboratory tests 7) Patients who have been using benzodiazepines for a long time 8) Patients with organic abnormalities in the brain who may not be able to properly measure EEG and BIS values 9) Patients scheduled to undergo epidural anesthesia / spinal anesthesia 10) Patients with cardiac pacemakers and ICDs 11) Lactating patients (except with the positive consent of the patient) 12) Other patients judged to be inappropriate by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1, ECG (RR interval, Tp-e, QTc time) 2, Blood pressure 3, Heart rate, pulse rate | — |
Countries
Japan
Contacts
Public ContactShota Tsukimoto
Kindai University Faculty of Medicine Dapartment of Anesthesiology
Outcome results
None listed