Healthy adult
Conditions
Interventions
Amino acids(4g, once a day, for 8 weeks)
Placebo(4g, once a day, for 8 weeks)
Sponsors
KSO corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female aged 20 or higher and less than 60 years old. 2. Individuals who have discomfort in knee joint and were diagnosed with 0 or I in K-L grade by principal investigator at the screening test. 3. Individuals who exercise more than 2 times a week. 4. Individuals who can make self-judgment and voluntarily provides written informed consent.
Exclusion criteria
Exclusion criteria: 1. Individuals who have a history of rheumatoid arthritis (RA) and have possibility of RA judged by blood marker test at the screening test. 2. Individuals who were diagnosed with osteoarthritis in need of a treatment by principal investigator. 3. Individuals who have implanted artificial joint, knee joint diseases such as meniscus injury or are under the treatment. 4. Individuals who are under medications which may affect knee joint such as poultice, ointment or painkiller. 5. Individuals who have received surgeries for chronic pain on the knee in the past. 6. Individuals who have severe chronic diseases (hepatic, cardiovascular, respiratory, endocrine, and metabolic disorders) 7. Individuals who are impossible to stop taking supplements or functional foods which may affect knee joint during this study. 8. Individuals who take amino acid -related medicines such as LIVACT, AminolebanEN and Hepan ED. 9. Individuals who regularly take amino acid/protein supplements. 10. Individuals who have amino acid metabolism disorders. 11. Individuals who are pregnant, lactating or have these plans. 12. Individuals who received more than 200 mL of blood collection within 12 weeks from the screening test. 13. Individuals who have participated in a study using other food intake or medicines, and cosmetics within one month retrospectively from the time of obtaining consent, or who are participating in other examinations during this study participation. 14. Individuals who are judged as unsuitable for the study by the investigator for the other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JOA score JKOM Knee range of motion | — |
Countries
Japan
Contacts
Public ContactYoshika Komori
KSO Corporation Sales Department
Outcome results
None listed