Healthy adults
Conditions
Interventions
Ingest a beverage containing plant extract once a day for 2 consecutive weeks ->
Wash out(4wks) ->
Ingest a beverage containing no plant extract once a day for 2 consecutive weeks.
Ingest a beverage containing no plant extract once a day for 2 consecutive weeks ->
Ingest a beverage containing plant extract once a day for 2 consecutive weeks.
Sponsors
Kao Corporation
Preferred Networks
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Healthy men and women aged 55 to 64 (2)Those who can take test foods and write a life diary
Exclusion criteria
Exclusion criteria: (1) During the test period, Subjects who may develop seasonal allergic symptoms such as pollinosis and may use medicines, or who are receiving medication related to it (2) Those who may have allergic symptoms to the test food. (3) Those who have had strokes due to cardiovascular disease (heart failure, angina, stroke, subarachnoid hemorrhage, etc.) or who are being treated. (4) Those with a history or signs of cerebrovascular disease or cardiovascular disease. (5) Those who suffering from liver disease, renal disease, respiratory disease, endocrine disorder, metabolic disorder, organ disorder, ventilation, rheumatism, autoimmune disease, psychiatric disease, cancer, infectious disease, etc. (6) Those with a history of gastrointestinal resection (excluding cecal resection) (7) Alcoholic drinkers (alcohol equivalent 60g / day or more) (8) Those who collected 200 mL of blood (donated blood, etc.) within 1 month or 400 mL or more within 3 months of the start of this study. (9) Those who have felt sick at the time of blood collection, or those who have difficulty in collecting blood because the blood vessels in the arm are difficult to see. (10) Those who are not day shifts such as night shifts and rotation shifts (11) Those who cannot take all the test foods (12) Those who have a history of vaccination (including influenza) 4 weeks before the start of the study (13) Within the last 2 weeks, those who have had mild wind symptoms such as fever, cough, sore throat (symptoms lasting more than 4 days), high fever, dyspnea, strong malaise, dysgeusia, or olfactory dysfunction or who have these now. (14) Those who have traveled abroad within one month (15) Those who plan to participate in other clinical trials during the trial participation period (16) Those deemed inappropriate to participate in this study by the principle investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of NK cell activity after continuous ingestion of plant extract-containing beverage for 2 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of IFN-g after continuous ingestion of plant extract-containing beverage for 2 weeks | — |
Countries
Japan
Contacts
Public ContactMai Umeda
Kao Corporation Biological Science Research laboratories
Outcome results
None listed