Phase 2 trial of Endoscopic Ultrasound guided Hepaticogastrostomy or Hepaticojejunostomy without Dilation for malignant biliary obstruction due to biliary and pancreatic cancer

Phase 2 trial of Endoscopic Ultrasound guided Hepaticogastrostomy or Hepaticojejunostomy without Dilation for malignant biliary obstruction due to biliary and pancreatic cancer - HURRICANE study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043977

Enrollment

Registered

2021-04-26

Start date

2021-04-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unresectable malignant biliary obstruction

Interventions

EUS-HGS/HJS without fistula dilation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Unresectable malignant biliary obstruction. 2) Unable to ERBD or EUS-CDS 3) Eligibility for EUS-HGS/HJS 4) One of the following conditions (1), (2), or (3) is met. (1) Total bilirubin >1.5 mg/dL, (2) AST >100 U/L, or (3) ALT >100 U/L. 5) No parenchymal jaundice. 6) No acute cholangitis with moderate or severe in the severity classification. 7) Hemoglobin level >= 8g/dL. 8) No bleeding tendency (platelets >= 50,000, prothrombin (PT) activity time >= 50%). 9) performance status (ECOG): 0, 1, 2 10) Age: 20 years or older. 11) Patient's written consent for participation in the study.

Exclusion criteria

Exclusion criteria: Judgement unsuitableness by the doctor.

Design outcomes

Primary

Measure	Time frame
Technical success	—

Countries

Japan

Contacts

Public ContactKosuke Maehara

National Cancer Center Hospital Department of Hepatobiliary and Pancreatic Oncology

kmaehara@ncc.go.jp03-3542-2511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026