Healthy adults
Conditions
Interventions
Daily ingestion of 4 capsules of test food for 12 weeks.
Daily ingestion of 4 capsules of dextrin for 12 weeks.
Sponsors
Hokkaido Information University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Subjects who fully understand significance, content and purpose of this study and who agree to participate in this study with a written informed consent. 2.Subjects with relatively low NK cell activity.
Exclusion criteria
Exclusion criteria: 1.Subjects who are under treatment or medication for autoimmune diseases, chronic inflammatory diseases, allergies, thrombocytopenia, and hypertension. 2.Subjects with serious cerebrovascular, cardiac, hepatic, renal, gastrointestinal diseases, and/or affected with infectious diseases requiring reports to the authorities. 3.Subjects with major surgical history relevant to the digestive system such as gastrectomy, gastrorrhaphy, enterectomy, etc. 4.Subjects with unusually high and/or low blood pressure and/or abnormal physical data and hematological data. 5.Subjects with severe anemia. 6.Pre- or post-menopausal women complaining of obvious physical changes. 7.Subjects who are at risk of having allergic reactions to drugs or foods (especially mushrooms). 8.Subjects who regularly take medicines, functional foods, and/or supplements which would affect the immune function. 9.Heavy smokers, alcohol addicts or subjects with disordered lifestyle. 10.Subjects who donated either 400 ml whole blood within 16 weeks (women), 12 weeks (men), 200 ml whole blood within 4 weeks (men and women), or blood components within 2 weeks (men and women), prior to the current study. 11.Subjects who currently participate in other clinical trials, or participated within the last 4 weeks prior to the current study. 12.Subjects determined to be ineligible by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NK cell activity at 4, 8, and 12 weeks after beginning the intake of test food. | — |
Secondary
| Measure | Time frame |
|---|---|
| IFN-gamma, the Brief Job Stress Questionnaire (Section B). | — |
Countries
Japan
Contacts
Public ContactNaoyuki HONMA
Hokkaido Information University Health Information Science Center
Outcome results
None listed