The effect of oral disinfectant containing iodine on thyroid function. Preliminary Study: Iodine intake from mouthwash and antiseptic solution.

The effect of povidone iodine (PVP-I) on thyroid function. Preliminary Study: Iodine intake from iodine mouthwash by gargling. - Iodine intake from PVP-I gargling or spraying.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043770

Enrollment

Registered

2021-03-29

Start date

2021-02-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid dysfunction

Interventions

Gargle by standarized method with mouthwash containing PVP-I or distilled water. Measure the amount and ratio of volume and iodine content in the fluid before and after gargling.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Heathy adults

Exclusion criteria

Exclusion criteria: Denture, oral cavity diseases, dysphagia

Design outcomes

Primary

Measure	Time frame
1. The absolute amount and ratio of mouthwash absorbed by standardized gargling. 2. The absolute amount and ratio of iodine absorbed by gargling.	—

Countries

Japan

Contacts

Public ContactYOZEN FUSE

Foundation for Growth Science Research committee on iodine related health problems

fuseyz@hotmai.com0358055370

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026