Esophageal cancer
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinically diagnosed as esophageal squamous cell carcinoma 2. Lesions mainly located in the cervical, thoracic, and abdominal esophagus 3. The lesion's depth of invasion is clinically diagnosed as EP/LPM or MM/SM1 4. No lymph node metastasis and no distant metastasis (cN0M0) 5. The entire circumferential lesion or sub-circumferential lesion (only in the case that become or expected to become the entire circumferential mucosal defect after ESD) 6. All multiple lesions are clinically diagnosed as MM/SM1 and spreading to less than 3/4 circumference of esophageal wall 7. Plaaned to perform with ESD, OPE, CRT, or RT in two months, or already performed within two weeks 8. No prior treatment of radiation therapy to the cervical chest, lung, or mediastinum field for any malignancies 9. No prior treatment for esophageal cancer, except for complete resection by EMR/ESD (shaollower than pT1a-MM without lympovascular invasion) and fulfilling the following (1) and (2) (1) The main lesion is located within 20 mm from the center of the scar after prior EMR/ESD (2) The ordinally endoscopy (diameter of 9.6-10.4 mm) could not pass the esophagus deu to the scar after prior EMR/ESD 10. 20 years or older 11. Written informed consent
Exclusion criteria
Exclusion criteria: Synchronous or metachronous (within 1 year) malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | — |
Countries
Japan
Contacts
National Cancer Center Hospital East, Kashiwa, Chiba, Japan Department of Gastroenterology and Endoscopy