Acute myocardial infarction
Conditions
Interventions
To observe intravascular status using optical coherence tomography and high-resolution coronary angioscopy continuously immediately after obtaining TIMI 3 flow.
Sponsors
Kansai Rosai Hospital Cardiovascular Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Twenty years of age or over at the time of informed consent 2) Singed informed consent after receiving the explanation about the study protocol 3) ST elevation myocardial infarction or non-ST elevation myocardial infarction 4) Arrival at the hospital within 12 hours from the onset of the symptom 5) Identifiable culprit lesion in a native coronary artery by coronary angiography
Exclusion criteria
Exclusion criteria: 1) Pregnancy 2) In-stent restenosis 3) Cardiogenic shock 4) Active bleeding complication 5) Participation or scheduled to participate to the other clinical trial or interventional study 6) Life expectancy within 1 year 7) Severe dementia 8) Severe chronic insufficiency or hemodialysis 9) Inappropriate to the study judged by investigators 10) Lesion in left main trunk 11) Previous history of old myocardial infarction 12) Impossible to obtain TIMI 3 flow before OCT and CAS evaluation 13) Impossible to perform sufficient observation by OCT or CAS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the findings between high-resolution coronary angioscopy (CAS) and optical coherence tomography (OCT) as follows: 1) CAS thrombus and OCT findings 2) Specific findings by CAS and OCT findings 3) Fibrous cap thickness by OCT and CAS findings | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the detection power between CAS and OCT as follows: 1) Morphology of acute myocardial infarction 2) Presence of thrombus 3) Presence of lipid-rich plaque | — |
Countries
Japan
Contacts
Public ContactTakuya Tsujimura
Kansai Rosai Hospital Cardiovascular Center
Outcome results
None listed