Analgesic effects of ultrasound-guided maxillary nerve block and inferior alveolar nerve block for upper and lower orthognathic surgery: a randomized controlled trial

Analgesic effects of ultrasound-guided maxillary nerve block and inferior alveolar nerve block for upper and lower orthognathic surgery: a randomized controlled trial - Analgesic effects of ultrasound-guided maxillary nerve block and inferior alveolar nerve block for upper and lower orthognathic surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043607

Enrollment

Registered

2021-03-13

Start date

2021-03-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vertical jaw deformities

Interventions

In the block group, bilateral ultrasound-guided maxillary and inferior alveolar nerve blocks are performed after induction of general anesthesia, and 5 mL each of 0.375% levobupivacaine is administere

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: over 16 years of age ASA-PS I to III undergoing upper and lower jaw plastic surgery

Exclusion criteria

Exclusion criteria: Patients who are allergic to the study drug, blood coagulation disorders, chronic opioid use, pregnancy, mental disorders, patients who were not extubated in the operating room after surgery for some reason, and other patients who, at the discretion of the physician in charge, are considered inappropriate for this study.

Design outcomes

Primary

Measure	Time frame
The number of times rescue analgesics are used in the 24 hours following the block.	—

Secondary

Measure	Time frame
After the block (1, 5, 15, 30, 60 min), levobupivacaine blood level, NRS at/after return, intraoperative opioid (fentanyl, remifentanil) use, pre-/postoperative QoR-40 scores, time to first analgesic use after discharge, complications of ner ve block (local anesthetic systemic toxicity, hematoma, local infection), respiratory complications in the first 24 hours after surgery	—

Countries

Japan

Contacts

Public ContactSho Kumita

Sapporo Medical University School of Medicine Department of Anesthesiology

todonotumari@me.com011-688-9663

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026