Healthy adult female
Conditions
Interventions
Apply the skin lotion and emulsion on facial skin for 4 weeks
Sponsors
ROHTO Pharmaceutical Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Healthy Japanese women who are between 30 and 49 years old 2. Subjects who are concerned about dryness, transparency, and dullness of the facial skin 3. Subjects who can give written informed consent of their own free will before this study
Exclusion criteria
Exclusion criteria: 1. Subjects with chronic skin conditions such as atopic dermatitis, or significant skin abnormalities of the face 2. Subjects with allergic symptoms or peculiar constitution to drugs or cosmetics 3. Subjects with current or history of cerebral nervous system disease, heart disease, psychiatric disease, or sleep-related disease 4. Subjects who are undergoing hormone replacement therapy for menopausal disorders or who have not been treated for at least 6 months 5. Pregnant or lactating women, or those who plan to become pregnant during the study period 6. Subjects who are participating in other clinical trials 7. Subjects who are judged ineligible by the study physician or the study director
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stratum corneum moisture content | — |
Secondary
| Measure | Time frame |
|---|---|
| Transepidermal water loss (0w, 4w, 8w) Skin image analysis Heart rate, Heart rate variability, Body surface temperature Environmental sensor Questionnaire | — |
Countries
Japan
Contacts
Public ContactSatoshi Inaoka
ROHTO Pharmaceutical Co., Ltd. Skin Care Product Development Division
Outcome results
None listed