Image study of the effect of Chinese herbal medicine on migraine and headache caused by pressure change

Imaging study on the efficacy of Chinese herbal medicine for migraine and primary headache induced by pressure change - Image study of Chinese herbal medicine for primary headache

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043584

Enrollment

Registered

2021-04-01

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine, headache due to pressure change

Interventions

Patients will first undergo rsfMRI, DTI, NODDI, T1 sagittal, and FLAIR imaging. After that, patients with migraine headache are started on Gosyuyuto and those with barometric headache are started on G

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects with a history of migraine or headache due to pressure change who understood the purpose of this study and gave consent

Exclusion criteria

Exclusion criteria: (1) Having an underlying disease and receiving treatment (2) Already taking Kampo medicines (Gosyuyuto, Goreisan or other) (3) During pregnancy (4) Currently participating or planning to participate in other clinical trials (5) Claustrophobia (6) Unsuitable for MRI imaging such as pacemaker or implant (7) Having been judged by the physician in charge to be inappropriate for participation in this study

Design outcomes

Primary

Measure	Time frame
Microstructure and brain functional connectivity in the treatment-responsive group after 2 months of oral medication	—

Countries

Japan

Contacts

Public ContactYasushi Shibata

Mito Kyodo General Hospital Neurosurgery

yshibata@md.tsukuba.ac.jp029-231-2371

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026