Analysis of microscopic structure and functional connectivity for headache with increasing intracranial pressure

Analysis of microscopic structure and functional connectivity for headache with increasing intracranial pressure - Analysis of headache with increasing intracranial pressure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043583

Enrollment

Registered

2021-04-01

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

increasing intracranial pressure

Interventions

First, resting state functional magnetic resonance imaging, DTI, NODDI, T1 sagittal, FLAIR axial, and ASL are performed in the horizontal supine position. The imaging time is just over 30 minutes. The

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adult who don't have chronic headache and intracranial disease

Exclusion criteria

Exclusion criteria: 1. Currently undergoing treatment for an underlying disease 2. Presence of organic intracranial lesions such as cerebrovascular disease or tumor 3. History of chronic headache 4. Pregnant 5.Currently participating or planning to participate in other clinical trials 6. claustrophobia 7. Inappropriate for MRI imaging such as pacemaker or implant

Design outcomes

Primary

Measure	Time frame
1.Headache pattern and intracranial pressure after starting HDBR 10min 2.Fractional Anisotropy (FA) and Functional Connectivity (FC) before and after starting HDBR	—

Countries

Japan

Contacts

Public ContactYasushi Shibata

Mito Kyodo General Hospital Neurosurgery

yshibata@md.tsukuba.ac.jp029-231-2371

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026