Malignant melanoma of skin and angiosarcoma of skin
Conditions
Interventions
Sponsors
National Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Primary cutaneous malignant melanoma or angiosarcoma No evidence of lymph node metastasis or distant metastasis (TNM classification T1-4N0M0 or rT1-4N0M0) Primary or local recurrence, refusal of surgery or no indication for radical surgery Refusal of drug therapy or no response to drug therapy (in case of malignant melanoma) Age between 20 and 85 years on the date of consent. ECOG performance status score of 0-2 Head and neck, chest, or extremity involvement Weight less than 95 kg
Exclusion criteria
Exclusion criteria: Obvious disseminated lesions The lesion has received radiotherapy in excess of 75 Gy. Active lesions/active multiple cancers other than the target lesion Active implantable medical devices such as implantable cardiac pacemakers are implanted History of BNCT treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of metabolites (including proteins) and genes in peripheral blood and urine to establish a measurement system for biomarkers of BNCT efficacy | — |
Countries
Japan
Contacts
Public ContactHiroshi Igaki
National Cancer Center Hospital Department of Radiation Oncology
Outcome results
None listed