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High-intensity signal on T1-weighted magnetic resonance imaging as a novel marker of intracoronary thrombus and intraplaque hemorrhage study

High-intensity signal on T1-weighted magnetic resonance imaging as a novel marker of intracoronary thrombus and intraplaque hemorrhage study - HISTOIRE study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000043533
Enrollment
100
Registered
2021-04-01
Start date
2021-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stable ischemic heart disease

Interventions

None listed

Sponsors

Department of cardiovascular medicine, Osaka city university graduate school of medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with stable ischemic heart disease diagnosed by tests including coronary computed tomography angiography undergoing elective percutaneous coronary intervention (PCI)

Exclusion criteria

Exclusion criteria: 1. Patients with acute coronary syndrome 2. Patients with prior PCI or coronary artery bypass grafting 3. Patients contraindicated to MR imaging 3a. Patients with claustrophobia 3b. Patients with pacemaker or implantable cardioverter defibrillator 3c. Patients judged as inappropriate for MR imaging by a treating physician 4. Patients who do not wish to participate in this clinical test 5. Patients judged as inappropriate by a treating physician

Design outcomes

Primary

MeasureTime frame
Association between biomarkers and the distribution of HIS

Secondary

MeasureTime frame
Clinical predictors for the change of HIS in non-target lesions during follow-up period; the association between the plaque characteristics on coronary computed tomography and the presence of HIS; the prognostic impact of the distribution of HIS at baseline.

Countries

Japan

Contacts

Public ContactMinoru Yoshiyama

Osaka city university graduate school of medicine Department of cardiovascular medicine

yoshiyama@med.osaka-cu.ac.jp06-6645-3801

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026