Comparison of reversal with neostigmine vs. sugammadex for postoperative bowel function in patients undergoing colorectal surgery

Comparison of reversal with neostigmine vs. sugammadex for postoperative bowel function in patients undergoing colorectal surgery - comparison of reversal with neostsigmine and sugammadex for post.op bowel function in patients undergoing colorectal surg.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043518

Enrollment

122

Registered

2021-09-14

Start date

2022-05-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal surgery

Interventions

sugammadex neostigmine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients in the American Society of Anesthesiology class 1 and 2 2. Patients planning colorectal surgery under general anesthesia 3. Patients with prior consent to the study

Exclusion criteria

Exclusion criteria: 1. Patients who have been given drugs that affect muscle relaxation recovery (anticonvulsants, antidepressants, etc.) 2. Patients who had history of neuromuscular diseases 3. Patients with hypersensitivity to rocuronium, neostigmine, and sugammadex 4. Patients with liver disease (OT/PT> 40 IU/L), kidney disease (Cr> 1.4 mg/dl) 5. Patients with with bowel obstruction 6. Patients who disagree with the test

Design outcomes

Primary

Measure	Time frame
Evaluating the time taken to expel gas in the first intestine after surgery	—

Countries

Asia(except Japan)

Contacts

Public ContactJIYOUN LEE

Seoul national university Bundang hospital Anesthesiology and pain medicine

heykiki1@hanmail.net+82317873640

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026