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Association of the simultaneous administration of Gingko biloba extract and absorption promoting agent with cognitive function

Efficacy of the mixture of Gingko biloba extract with Sesame extract and Turmeric oil on cognitive function in healthy adults: a 24 weeks, randomized double-blind, placebo-controlled trial - Association of "Gingko biloba extract with Sesame extract and Turmeric oil" with cognitive function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000043494
Enrollment
159
Registered
2021-05-01
Start date
2021-10-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Two capsules of GBE/MST supplement, once a day for 24 weeks Two capsules of GBE supplement, once a day for 24 weeks Two capsules of placebo, once a day for 24 weeks

Sponsors

Department of Aging Research and Geriatric Medicine IDAC, Tohoku University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy adults who is confirmed with a written informed consent. Normal cognitive function at baseline is confirmed by Montreal Cognitive Assessment battery Japanese version (more than 26).

Exclusion criteria

Exclusion criteria: 1) With past history of severe neurological diseases. 2) With critical bleeding incidents. 3) Use of antithrombotic medicine. 4) Severe depression 5) Patients with diabetes mellitus. 6) With severe visual or auditory disability. 7) Individuals with any metal implantation, such as cardiac pacemaker, coronary stent and artificial joint. 8) Claustrophobia. 9) Use of any supplement. 10) Creatinine clearance less than 15ml/min. 11) Patients with gastrointestinal diseases or metabolic diseases. 12) Diagnosed psychiatric disorders. 13) Participants who cannot obtain the informed consent. 14) Allergy to the study materials. 15) Individuals who is not suitable for participating in this study decided by principal investigator.

Design outcomes

Primary

MeasureTime frame
The primary endpoint of this study is to discover any alteration of cognitive function in healthy adults assessed by Wechsler Memory Scale revised (WMS-R) following 24 weeks administration of GBE/MST.

Countries

Japan

Contacts

Public ContactTaizen Nakase

IDAC, Tohoku University Department of Aging Research and Geriatric Medicine

taizen.nakase.a4@tohoku.ac.jp022-717-8559

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026