Efficacy of physiological left bundle branch area pacing in patients with bradycardia and heart failure

Efficacy of physiological left bundle branch area pacing in patients with bradycardia and heart failure - Efficacy of physiological left bundle branch area pacing

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043493

Enrollment

100

Registered

2021-03-04

Start date

2019-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To investigate the efficacy and complication of the physiological left bundle branch area pacing

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Permanent pacing indication class I and IIa for bradycardia or conduction system disturbance. 2) Cardiac resynchronization therapy indication class IIa in patients with atrioventricular block, left ventricular ejection fraction of 36-50% and pacing dependency. 3) Cardiac resynchronization therapy indication class I- IIa in patients with left ventricular ejection fraction of <36% and failure of left ventricle pacing and non-responder for cardiac resynchronization therapy

Exclusion criteria

Exclusion criteria: age of less than 20 years-old

Design outcomes

Primary

Measure	Time frame
Successful implantation of physiological left bundle branch area pacing lead and complications during more than six months	—

Secondary

Measure	Time frame
1)Comparison of electrical propagation in the conduction system and ventricle between the His-bundle pacing and left bundle branch area pacing. 2) Identification of predictors for successful implantation of left bundle branch area pacing lead. 3) Cardiac function during left bundle branch area pacing.	—

Countries

Japan

Contacts

Public ContactToshiaki Sato

Kyorin University,Medical school Division of Advanced Arrhythmia Management

toshiaki_sato@ks.kyorin-u.ac.jp0422-47-5511

Outcome results