Molecular biological study to elucidate pathogenicity of epicardial adipose tissue

Molecular biological study to elucidate pathogenicity of epicardial adipose tissue - Molecular biological study of epicardial adipose tissue

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043455

Enrollment

Registered

2021-02-27

Start date

2021-02-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) patients aged >= 30 years old 2) patients scheduled for elective coronary artery bypass graft surgery or cardiac valve surgery 3) patients undergoing echocardiography and cardiac catheter test within 3 months before cardiac surgery 4) patients undergoing cardiac CT and/or cardiac magnetic resonance within 3 months before cardiac surgery 5) patients who agree with informed consent

Exclusion criteria

Exclusion criteria: 1) critical conditions, such as immediately after brain hemorrhage 2) acute coronary syndrome, critical heart failure, and shock status 3) pregnant or breast-feedings women

Design outcomes

Primary

Measure	Time frame
(1) Immunohistological characteristics and expression levels of cytokines in epicardial adipose tissue based on the classification and severity of heart diseases (2) Clinical imaging markers related to immunohistological abnormalities and cyotokine expressions in epicardial adipose tissue	—

Countries

Japan

Contacts

Public ContactToshiro Kitagawa

Hiroshima University Graduate School of Biomedical and Health Sciences Department of Cardiovascular Medicine

toshirok@hiroshima-u.ac.jp082-257-5555

Outcome results