Effect of lactulose ingestion on ammonia gas emitted from human skin.

Effect of lactulose ingestion on ammonia gas emitted from human skin. - Effect of lactulose ingestion on ammonia gas emitted from human skin.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043445

Enrollment

Registered

2021-02-26

Start date

2021-02-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Single intake of 4g lactulose Single intake of placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy people

Exclusion criteria

Exclusion criteria: 1) Subjects with severe hepatic, renal, heart, gastrointestinal, cerebrovascular, endocrine, metabolic or infection diseases. 2) Subjects with the history of gastrointestinal resection. 3) Subjects with gastrointestinal dysfunction such as irritable bowel syndrome or inflammatory bowel disease. 4) Subjects who use medicines or supplements that may influence feces frequency; e.g. antibiotics, probiotics, laxatives, antidiarrheals, fibers. 5) Subjects with milk allergy, metal allergy, or lactose intolerance. 6) Subjects who participate another study. 7) Subjects who are judged inappropriate for the study by the investigator or the physician.

Design outcomes

Primary

Measure	Time frame
Emission flux of Ammonia gas from human skin (AUC)	—

Secondary

Measure	Time frame
Emission flux of Ammonia gas from human skin (Peak value), Stool forms	—

Countries

Japan

Contacts

Public ContactYoshika Sekine

Tokai University Graduate School of Science

sekine@keyaki.cc.u-tokai.ac.jp0463-58-1211

Outcome results