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The Effect of Vitamin C Supplementation on Plasma Vitamin C levels after Scaling and Rootplaning in Periodontitis-Smokers

The Effect of Vitamin C Supplementation on Plasma Vitamin C Levels after Scaling and Rootplaning in Periodontitis-Smokers - The Effect of Vitamin C Supplementation on Plasma Vitamin C Levels after Scaling and Rootplaning in Periodontitis-Smokers : Vitamin C Supplementation on Plasma Vitamin C levels after SRP in Periodontitis-Smokers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000043365
Enrollment
30
Registered
2021-12-20
Start date
2019-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy-adult smokers, with chronic periodontitis

Interventions

The test group received scaling and rootplaning and 320 mg vitamin C (Ester C) once a day, 30 days before and after scaling and rootplaning (in total 60 days of supplementation) The control group rece

Sponsors

Dental Faculty - Universitas Padjadjaran Indonesia Periodontology Departement
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Systemically healthy adults; 2. > 30 years old and < 65 years old; 3. Being a smoker (10 cigarettes/day for more than 5 years); 4. Having chronic periodontitis (having pocket depth more than 5 mm at least at 2 teeth in maxilla and/or mandible)

Exclusion criteria

Exclusion criteria: 1. had a systemic disease; 2. had a course of non steroidal anti inflammatory drugs or antimicrobial drugs within a 3-month period before the study began; 3. were pregnant or lactating; 4. used mouth-washes or vitamin supplements within the previous 3 months; 5. underwent periodontal treatment within a 3-month period before study began; 6. were using any orthodontic or prosthodontic appliances.

Design outcomes

Primary

MeasureTime frame
Plasma Vitamin C Levels

Secondary

MeasureTime frame
Periodontal Probing depth

Countries

Asia(except Japan)

Contacts

Public ContactAmaliya Amaliya

Dental Faculty - Universitas Padjadjaran - Indonesia Periodontology

amaliya@fkg.unpad.ac.id0062222504985

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026