Development and validation of a clinical prediction model for psychotic relapse within 12 months after discharge in people with schizophrenia

Development and validation of a clinical prediction model for psychotic relapse within 12 months after discharge in people with schizophrenia - Development and validation of a clinical prediction model for psychotic relapse within 12 months after discharge in people with schizophrenia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043345

Enrollment

800

Registered

2021-02-20

Start date

2020-12-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia and related disorders

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who were discharged from one of five participating hospitals between January 2014 and December 2018 will be included if they were diagnosed as one of the following (ICD-10 code in the parentheses): - Schizophrenia (F20) - Schizotypal disorder (F21) - Persistent delusional disorders (F22) - Acute and transient psychotic disorders (F23) - Induced delusional disorder (F24) - Schizoaffective disorders (F25) - Other nonorganic psychotic disorders (F28) - Unspecified nonorganic psychosis (F29)

Exclusion criteria

Exclusion criteria: Patients with the following conditions will be excluded: - Those who had been enrolled in this study with a previous episode of hospitalisation due to psychosis (i.e. a patient cannot be enrolled more than once during the study period) - Those with substance/medication-induced psychosis - Those with psychosis due to another medical condition, including peri-and postpartum psychosis and psychosis in dementia - Those with diagnosis in the inclusion criteria whose admission are not due to psychosis as judged by one of investigators - Those with diagnosis in the inclusion criteria with which one of investigators disagree due to the lack of sound reasoning - Those discharged from a non-acute ward - Those with a plan to be readmitted in the short period of time - Those with ambiguous diagnosis as judged by one of investigators - Those discharged to another psychiatric hospital - Those discharged to medical hospital

Design outcomes

Primary

Measure	Time frame
Psychotic relapse as a composite outcome defined by an occurrence of any one of the following: psychiatric hospitalisation, psychiatrist's decision that hospitalisation is required, an increase in antipsychotic dosage, an increase in the level of psychiatric care, and violence to self and/or others. Participants will be followed up up to 12 months after their discharge from the index hospitalisation.	—

Measure

Time frame

Psychotic relapse as a composite outcome defined by an occurrence of any one of the following: psychiatric hospitalisation, psychiatrist's decision that hospitalisation is required, an increase in antipsychotic dosage, an increase in the level of psychiatric care, and violence to self and/or others. Participants will be followed up up to 12 months after their discharge from the index hospitalisation.

—

Secondary

Measure	Time frame
Psychiatric hospitalisation due to psychotic relapse	—

Countries

Japan

Contacts

Public ContactAkira Sato

Kyoto University School of Medicine Department of Health Promotion and Human Behavior

sato.akira.57m@st.kyoto-u.ac.jp080-3475-7068

Outcome results