Investigation of the efficacy by modified thoracoabdominal nerves block perichondrial approach (M-TAPA) in laparoscopic gynecological surgery - Comparison with the oblique subcostal transversus abdominis plane block : a pilot randomized controlled trial

Investigation of the efficacy by modified thoracoabdominal nerves block perichondrial approach (M-TAPA) in laparoscopic gynecological surgery - Comparison with the oblique subcostal transversus abdominis plane block : a pilot randomized controlled trial - Investigation of the efficacy by modified thoracoabdominal nerves block perichondrial approach (M-TAPA) in laparoscopic gynecological surgery - Comparison with the oblique subcostal transversus abdominis plane block : a pilot randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043336

Enrollment

Registered

2021-03-01

Start date

2021-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic diseases such as uterine malignancies, uterine fibroids, and adenomyosis

Interventions

modified thoracoabdominal nerves block through perichondrial approach oblique subcostal transverse abdominis plane block

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients scheduled laparoscopic hysterectomy at Nara Medical University Hospital

Exclusion criteria

Exclusion criteria: Rejection Communication difficulty Chronic opioid use (Daily use or usage morphine equivalent more than 60mg per day within 1 month before surgery) Skin disease at puncture site Allergy to local anesthetics Coagulation disorder Patients who have received antithrombotic therapy and conflict with a sufficient period of drug withdrawal according to the guideline published by JSA/JSRA/JSPC Body weight < 42 kg BMI > 35 Visit restrictions due to prevention for COVID-19 Judged inappropriate by the investigator

Design outcomes

Primary

Measure	Time frame
Quality Recovery 15 (QoR-15) score at the day before surgery and 48 hours after surgery	—

Secondary

Measure	Time frame
Numerical rating scale (NRS) at 2/12/24/48 hours after surgery Measurement of blood concentration of levobupivacaine at 15/30/45/60/120 minutes after block enforcement Time to request the first bolus on the patient controlled analgesia after surgery Frequency of non-opioid analgesic use Occurrence of postoperative nausea and vomiting	—

Countries

Japan

Contacts

Public ContactTakanori Suzuka

Nara Medical University Department of Anesthesiology

szk.tknr.0825@naramed-u.ac.jp0744-22-3051

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026