Study on the effect of catechin gel on oral tissues (mainly periodontal tissues)

Efficacy of catechin gel as a local drug delivery for patients with periodontitis - Efficacy of catechin gel for periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043302

Enrollment

Registered

2021-02-10

Start date

2015-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Placebo gels were topically administered (0.5 ml) once a month for three times into the periodontal pockets of patients with periodontitis. Catechin gels (2.75 mg/ml) were topically administered (0.5

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Systemically healthy, 2) Non-smoker, 3) No history of antibiotic therapy and use of antiseptics in the last six months, 4) Having one or more interproximal sites, 5) Patients who had at least two teeth having PPD 5 mm with attachment loss, 6) Radiographic evidence of alveolar bone loss.

Exclusion criteria

Exclusion criteria: Known or suspected allergies to the food or drugs.

Design outcomes

Primary

Measure	Time frame
With baseline at the end of initial periodontal therapy, placebo gel, catechin gel or minocycline gel was topically administered into the periodontal pocket at a depth of 5 mm or more at baseline, 1 month after final administration. Compare the probing depth with the baseline.	—

Secondary

Measure	Time frame
Bacterial test in periodontal pocket	—

Countries

Japan

Contacts

Public Contactmasaki Tamatsu

Nihon University School of Dentistry at Matsudo Research Office

tamatsu.masaki@nihon-u.ac.jp047(360)9273

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026