Effect of preceding inspiration method and cough timing on coughing power

Research on effect of preceding inspiration method and cough timing on coughing power - Research on effect of preceding inspiration method and cough timing on coughing power

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043290

Enrollment

Registered

2021-02-15

Start date

2021-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive ventilatory disturbance, Restrictive ventilatory disturbance

Interventions

Coughing power test For this measurement, the spirometer will be attached to a mask for expiratory gas analysis. The coughing power(peak cough flow:PCF) is measured under the following four condition

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy subject 1) Healthy subjects over 20 years old 2) Subjects who can give consent in writing for participation in this study 3) Non-smokers or light smokers with a Brinkman index of less than 100 Respiratory disease patients 1) Patients aged over 20 years old 2)Patients who can give consent in writing for participation in this study 3) Patients who are outpatients at Gunma University Hospital 4) Patient with restrictive ventilation disorder or obstructive ventilation disorder

Exclusion criteria

Exclusion criteria: 1)Patients with unexplained blood sputum 2) Patients diagnosed with angina pectoris 3) Patients suffering from unstable cardiovascular disease 4) Patients diagnosed with myocardial infarction or pulmonary embolism 5) Patients with aortic aneurysm 6) Patients immediately after eye surgery (cataract or glaucoma) 7) Patients who have undergone thoracic or abdominal surgery 8) Patients who are unable to give explanation and consent due to cognitive function or psychiatric symptoms

Design outcomes

Primary

Measure	Time frame
Peak cough flow	—

Secondary

Measure	Time frame
Forced Vital Capacity Percent predicted Forced Vital Capacity Forced Expiratory Volume in 1 second Percent predicted Forced Expiratory Volume in one second Forced Expiratory Volume in 1 second as percent of FVC Percent predicted Forced Expiratory Volume in 1 second as percent of FVC Maximal Voluntary Ventilation Percent predicted Maximal Voluntary Ventilation Peak Expiratory Flow Percent predicted Peak Expiratory Flow V75-25 Percent predicted V75-25 Peak inspiratory Flow	—

Measure

Time frame

Forced Vital Capacity Percent predicted Forced Vital Capacity Forced Expiratory Volume in 1 second Percent predicted Forced Expiratory Volume in one second Forced Expiratory Volume in 1 second as percent of FVC Percent predicted Forced Expiratory Volume in 1 second as percent of FVC Maximal Voluntary Ventilation Percent predicted Maximal Voluntary Ventilation Peak Expiratory Flow Percent predicted Peak Expiratory Flow V75-25 Percent predicted V75-25 Peak inspiratory Flow

—

Countries

Japan

Contacts

Public ContactTakeshi Hisada

Gunma University Graduate School of Health Sciences / Department of Respiratory Medicine and Allergy

hisadat@gunma-u.ac.jp027-220-8944

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026