Effect of the combined ingestion of plant-derived ingredients on the pharmacokinetic parameter

Effect of the combined ingestion of plant-derived ingredients on the pharmacokinetic parameter - Effect of the combined ingestion of plant-derived ingredients on the pharmacokinetic parameter

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043278

Enrollment

Registered

2021-02-08

Start date

2016-04-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

control (1) &gt

wash out &gt

control (2) &gt

test beverage (1) &gt

test beverage (2) &gt

test beverage (3) control (2) &gt

test beverage (3) &gt

control (1) test beverage (1) &gt

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy males BMI <= 18.5 and >= 29.9

Exclusion criteria

Exclusion criteria: 1) history of or under treatment for gastrointestinal disorder 2) under treatment for severe disease 3) taking therapeutic medicine 4) TG > 399mg/dL, T-Cho > 259mg/dL, FBG 125mg/dL > and HbA1c > 6.4%, AST > 50U/L, ALT > 50U/L, g-GTP > 100U/L 5) HBs positive, HCV positive 6) creatinine > 1.29mg/dL, BUN > 22.0mg/dL 7) syphilis positive, HIV positive 8) food allergy 9) shift worker 10) blood donor (> 200 mL within the last month or > 400 mL within the last 3 months) 11) heavy drinker 12) heavy smoker 13) drinking less than 2 cups of tea or coffee per day 14) Subjects who are judged to be inappropriate for the study by the medical doctor

Design outcomes

Primary

Measure	Time frame
Evaluation of the pharmacokinetic parameter after the single ingestion. (AUC)	—

Secondary

Measure	Time frame
Evaluation of the pharmacokinetic parameter after the single ingestion. (Cmax, Tmax)	—

Countries

Japan

Contacts

Public ContactSachiko Oishi

Kao Corporation Biological Science Research

oishi.sachiko@kao.com+81-3-5630-7266

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026