Healthy male/female adults
Conditions
Interventions
Oral ingestion of pro/prebiotics for 12 weeks.
Oral ingestion of probiotics for 12 weeks.
Oral ingestion of prebiotics for 12 weeks.
Oral ingestion of placebo for 12 weeks.
Sponsors
CPCC Company Limited
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Male/female subjects ranging in age from 20 to 64 at informed consent. 2) Subjects ranging in BMI from 25.0 to <30.0 kg/m2. 3) Subjects who can give informed consent to participate in this trial after being provided with an explanation of the experimental protocol detail.
Exclusion criteria
Exclusion criteria: 1) Subjects with previous/present medical history of serious diseases. 2) Subjects who contracted a digestive disease within the past two weeks, and are now under medical treatments. 3) Subjects with medical therapies for a lifestyle-related disease, such as diabetes, hypertension and dyslipidemia. 4) Subjects with milk allergy or suspicious one. 5) Pregnant, possibly pregnant during this trial, or lactating women. 6) Subjects falling into the habit of heavy smoking, excessive alcohol intake, and/or an irregular life rhythm. 7) Subjects taking steadily (not less than three times a week) in the health foods, probiotics, prebiotics, fermented milk and/or lactic acid beverages, which might affect the test results. 8) Subjects who took part in the other clinical/monitoring tests, except observing ones, within a month before giving informed consent to take part in this trial. 9) Others who have been determined as ineligible for participation in this trial, judging from the principal/sub investigator's opinions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Visceral fat area 2. Body fat percentage 3. Body fat mass 4. Body weight 5. Body mass index 6. Gut microbiota 7. Short chain fatty acids in blood and feces (acetic/propionic/n-butyric/iso-butyric/n-valeric/iso-valeric acids) 8. Gastrointestinal hormones (PYY, GLP-1, GIP, insulin) 9. Blood-biochemical test (Total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, blood glucose, and HbA1c) | — |
Countries
Japan
Contacts
Public ContactMakoto Ichinohe
CPCC Company Limited Clinical Planning Department
Outcome results
None listed