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A cross-sectional study on measuring amino acids in fatty liver

A cross-sectional study on the significance of measuring amino acids in understanding the pathogenesis of non-alcoholic fatty liver disease - A study to measure amino acids in non-alcoholic fatty liver disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000043266
Enrollment
500
Registered
2021-02-08
Start date
2021-02-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-alcoholic fatty liver disease

Interventions

None listed

Sponsors

Department of Gastroenterology and Hepatology, Yokohama City University Hospital
Lead Sponsor
Drug Discovery Department, Chemistry Research Group, EA Pharma Co., Ltd
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who have been diagnosed with NAFLD by histological or imaging studies within 6 months. Patients who have not been diagnosed with NAFLD by imaging studies such as ultrasonography and MRI within 6 months.

Exclusion criteria

Exclusion criteria: Patients who have used antimicrobial agents within one month of blood and stool specimen collection Patients who have been diagnosed with infectious hepatitis (hepatitis B or C, HIV infection), autoimmune hepatitis, primary biliary cirrhosis, sclerosing cholangitis, hemochromatosis, alpha1-antitrypsin deficiency, Wilson's disease, drug-induced hepatitis, alcoholic hepatitis, or are known to consume excessive amounts of alcohol Patients who are unable to collect specimens due to defecation disorder. Patients who do not wish their medical information to be used for research purposes. Patients who are judged by the physician to be unsuitable for the study.

Design outcomes

Primary

MeasureTime frame
Comparison of serum and fecal amino acid concentrations between NAFLD and non-NAFLD patients

Countries

Japan

Contacts

Public ContactMichihiro Iwaki

Yokohama City University Hospital Department of Gastroenterology and Hepatology

michihir@yokohama-cu.ac.jp0457872800

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026