Prospective sampling, multicentre study to investigate the association between background data and the intestinal environment in patients with diverticulosis of the colon and non-diverticulosis (healthy subjects and patients with chronic intestinal pseudo-obstruction, constipation or diarrhoea etc).

Prospective sampling, multicentre study to investigate the association between background data and the intestinal environment in patients with diverticulosis of the colon and non-diverticulosis (healthy subjects and patients with chronic intestinal pseudo-obstruction, constipation or diarrhoea etc). - Study to investigate the association between background data and the intestinal environment in patients with diverticulosis of the colon and non-diverticulosis (healthy subjects and patients with chronic intestinal pseudo-obstruction, constipation or diarrhoea etc).

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043262

Enrollment

500

Registered

2021-02-05

Start date

2021-02-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with diverticula, those without diverticula (healthy individuals or those with chronic intestinal pseudo-obstruction, diarrhoea, constipation, etc.)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) 20 years old or older at the time of registration (2) Gender is not required (3) Patients with a medical record (4) Patients who can provide written consent for participation in this study

Exclusion criteria

Exclusion criteria: (1) Patients who cannot collect specimens due to defecation disorder (2) Other patients who are judged by the physician to be unsuitable for the study.

Design outcomes

Primary

Measure	Time frame
Total bile acid concentration in stool	—

Secondary

Measure	Time frame
Stool metabolites, stool markers, gut microbiota, blood metabolites, blood markers, QOL (e.g. SF-36), QOL/questionnaire (NRS, PAC-QOL, PAC-SYM, GSRS, etc.), frequency of each disease, risk factors.	—

Countries

Japan

Contacts

Public ContactAyako Ujiie

Yokohama city university Gastroenterology and hepatology

kessoku-tho@umin.ac.jp0457872640

Outcome results