Measurement of intestinal permeability using lactulose and mannitol test

Measurement of intestinal permeability using lactulose and mannitol test - Measurement of intestinal permeability using lactulose and mannitol test

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043247

Enrollment

750

Registered

2021-02-07

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal disease

Interventions

Sugar tolerance test: After a single dose of sugar solution (lactulose 10g, mannitol 5g), collect urine after 6hours.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 20<= 80> year-old females and males 2. Subject must read and sign the informed consent form

Exclusion criteria

Exclusion criteria: 1. Presence of galactosemia 2. Presence of an allergy to food containing sugar alcohol 3.Diabetic patients with poor glycemic control 4.Patients who do not consent to participate in this study 5. Determined ineligible by the principal investigator or sub-investigator

Design outcomes

Primary

Measure	Time frame
To investigate the frequency and severity of intestinal barrier dysfunction and its association with prognosis in each disease	—

Countries

Japan

Contacts

Public ContactAki Sakatani

Asahikawa Medical University Gastroenterological Pathophysiology

sakatani@asahikawa-med.ac.jp0166-68-2462

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026