Healthy adults
Conditions
Interventions
Take 1 packet of test food (low dose)daily with water before breakfast
Take 1 packet of test food (high dose)daily with water before breakfast
Take 1 packet of placebo daily with water before breakfas
Sponsors
Jabara Laboratory Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age between 20 and 65 years at the time of informed consent. 2. Japanese male or female 3. having symptoms of discomfort such as itchy eyes, runny nose, and stuffy nose due to dust, house dust, pollen, etc., but healthy and having no chronic physical illness 4. not having allergic drugs before and during the test (for healthy case), or taking allergic drugs occasionally before and during the test (not regularly)(for mild case) 5. BMI of less than 30 kg/m2 6. Not smoker (not electronic cigarette smoker) 7. Those who are able to input electronic diary with smartphone / PC. 8. Those who received sufficient explanation about the trial, volunteered to participate after understanding the purpose, and agree to participate in the trial with written consent.
Exclusion criteria
Exclusion criteria: 1. severe or most severe classification of allergic rhinitis symptoms 2. acute rhinitis, sinusitis, nasal polyps, hypertrophic rhinitis, nasal septum deviation 3. bronchial asthma 4. severe liver, heart, kidney, respiratory, endocrine and metabolic diseases 5. current or history of specific desensitization therapy 6. receiving some kind of drug for treatment 7. current or history of drug allergies or food allergies 8. history of discomfort or problems with physical symptoms after eating citrus fruits 9. consumption of food for specified health use or foods with functional claims 10. pregnant or lactating, or willing to be pregnant during the trial 11. experience of feeling sick due to blood collection, or told that blood vessels are thin at the time of blood collection 12. participation in another clinical trial within one month of enrollment into the trial, participating currently or planning to participate 13. possible changes of their lifestyle, such as long trip, etc. during the study 14. alcohol consumption of >60g equivalent 15. irregular diet, shift worker, night shift, irregular life rhythm 16. judged by the investigator to be unsuitable for participating in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Japan Allergic Rhinitis Standard QOL Questionnaire (JRQLQ No1) | — |
Secondary
| Measure | Time frame |
|---|---|
| Japan Allergic Rhinitis Standard QOL Questionnaire (JRQLQ No1) overall score Nose / Eye Symptom Questionnaire Intranasal evaluation | — |
Countries
Japan
Contacts
Public ContactSeisho Azuma
Jabara Laboratory Co., Ltd. CEO
Outcome results
None listed