A prospective observational study of the effects of various valves on coagulation factors and platelet function after transcatheter aortic valve replacement

A prospective observational study of the effects of various valves on coagulation factors and platelet function after transcatheter aortic valve replacement - A prospective observational study of the effects of various valves on coagulation factors and platelet function after transcatheter aortic valve replacement

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043199

Enrollment

Registered

2021-02-01

Start date

2021-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe aortic stenosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed with aortic stenosis and undergoing transcatheter aortic valve implantation using The Edwards Lifesciences' SAPIEN3 or The Medtronic's Evolute-R at Teikyo University hospital

Exclusion criteria

Exclusion criteria: 1) Patients who did not consent to participate in this study 2) Cases converted to open heart surgery during TAVI 3) Cases of massive bleeding during surgery 4) Perioperative Fresh frozen plasma or platelet transfusion 5) Non elective surgery 6) Cases where the planned valves were suddenly changed 7) Recognized coagulation system disorders before enrollment 8) TAVI with approaches other than Trans-Femoral 9) Cases with other severe valve diseases

Design outcomes

Primary

Measure	Time frame
R(min)<TEG6s> [Evaluation of coagulation factors] MA(min)<TEG6s> [Evaluation of platelet function]	—

Countries

Japan

Contacts

Public ContactTakeyuki Sajima

Teikyo University Hospital Department of Anesthesiology

sajitake0331@yahoo.co.jp03-3964-1211

Outcome results