Is keratinized mocosa essential to the health of dental implants: In search of microbiological evidence.

Is keratinized mocosa essential to the health of dental implants: In search of microbiological evidence. - Is keratinized mocosa essential to the health of dental implants: In search of microbiological evidence.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043181

Enrollment

Registered

2021-02-01

Start date

2019-07-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missing teeth

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Subjects with an indication for dental implant treatment who consent to the operation (both maxilla and mandible can be included). 2)Subjects with a first-person voluntary consent to participate in this clinical study, which can be obtained in writing (inpatients, outpatients, or both gender can be included). 3)Subjects aged 20 and above, at the time of a written consent.

Exclusion criteria

Exclusion criteria: 1)The exclusion criteria for study device. (1)Patients with hemorrhagic diathesis. (2)Patients with metabolic or endocrine diseases that may significantly affect postoperative bone formation (severe osteoporosis and others). (3)Patients taking steroids that may affect the postoperative healing of tissues. (4)Patients with uncontrolled diabetes. (5)Patients with strong bruxism or in overloading condition. (6)Patients known to be allergic to the metal (titanium alloy) used in this product. (7)Patients with a history of radiotherapy at the site of implantation. (8)Patients for whom postoperative care cannot be controlled such as the following: - Patients with dementia or other mental disabilities - Patients with drug addiction - Patients with alcoholism (9)Patients with insufficient width and height of bone (bone mass) around the implant (patients who need combination therapy of bone prosthetic materials). (10)Patients with serious cardiovascular disease such as myocardial infarction. (11)Pregnant or breast-feeding patients. (12)Other patients who are not adequate to participate this study. *Additionally, the exclusion criteria for clinical study.

Design outcomes

Primary

Measure	Time frame
Bacterial species composing the microbiota	—

Countries

Japan

Contacts

Public ContactMasaki Shibasaki

Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Oral Implantology and Regenerative Dental Medicine

shibirm@tmd.ac.jp03-5803-5773

Outcome results