Colonoscopic Randomized Clinical Trial for TXI-use additional 30-seconds observation for preventing missed polyps

Colonoscopic Randomized Clinical Trial for TXI-use additional 30-seconds observation for preventing missed polyps - COLT-30 study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043178

Enrollment

370

Registered

2021-03-01

Start date

2021-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal polyps

Interventions

TXI observation for additional 30 secs observation NBI observation for additional 30 secs observation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: age over 40 years 1. various symptoms such as abdominal pain, constipation, anemia, and hematochezia 2. surveillance after polyp or cancer resection 3. positive fecal occult blood 4. screening

Exclusion criteria

Exclusion criteria: 1) surgical resection of right-sided colon 2) Familial adenomatous polyposis 3) Inflammatory bowel syndrome

Design outcomes

Primary

Measure	Time frame
neoplastic polyp number (adenoma and sessile serrated lesion) per patient detected with additional 30-seconds observation of TXI and NBI	—

Secondary

Measure	Time frame
In the TXI and NBI groups, polyp detection rate with additional 30-seconds observation adenoma and sessile serrated lesion number with additional 30-seconds observation adenoma and sessile serrated lesion detection rate with additional 30-seconds observation The increase of adenoma and sessile serrate lesions in first and second observation compared to first observation The efficacy of addtional 30 seconds observation according to status of bowel preparation, types of endoscopes, endoscopist lvel	—

Measure

Time frame

In the TXI and NBI groups, polyp detection rate with additional 30-seconds observation adenoma and sessile serrated lesion number with additional 30-seconds observation adenoma and sessile serrated lesion detection rate with additional 30-seconds observation The increase of adenoma and sessile serrate lesions in first and second observation compared to first observation The efficacy of addtional 30 seconds observation according to status of bowel preparation, types of endoscopes, endoscopist lvel

—

Countries

Japan

Contacts

Public ContactNaohisa Yoshida

Kyoto Prefectural University of Medicine Molecular Gastroenterology and Hepatology

naohisa@koto.kpu-m.ac.jp075-251-5519

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026