Changes in the number of Streptococcus mutans after intake of Lactobacillus rhamnosus L8020-containing tablets

Changes in the number of Streptococcus mutans after intake of Lactobacillus rhamnosus L8020-containing tablets - Changes in the number of Streptococcus mutans after intake of L8020-containing tablets

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043171

Enrollment

100

Registered

2021-01-29

Start date

2021-01-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Volunteers ingest one L8020-containing tablet every day after dinner for 4 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy adult without dental caries, gingivitis and periodontal disease 2. Subject who will be able to prohibit other L8020 products during experiment period 3. Subject who provides written informed consents

Exclusion criteria

Exclusion criteria: 1. Subject with allergy to dairy products 2. Subject with a history of antibiotic treatment within a month before experiment 3. Subject who may receive oral treatment of topical fluoride during experiment period 4. Subjects who may be newly treated with povidone-iodine during experiment period

Design outcomes

Primary

Measure	Time frame
Changes in the distribution of semi-quantitative values of the number of Streptococcus mutans 4 weeks after intake	—

Countries

Japan

Contacts

Public ContactMasae Kitagawa

Hiroshima University Hospital Center of Oral Clinical Examination

mhiraoka@hiroshima-u.ac.jp082-257-5727

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026