Sepsis and Platelet microRNA

Potential mechanisms and its microRNA interactions of platelet reductions in patients with sepsis-induced coagulopathy (Prospective obserbational study) - Role of platelet microRNA in the pathogenesis of sepis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043130

Enrollment

115

Registered

2021-01-25

Start date

2019-06-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with and without sepsis admitted to the ICU

Exclusion criteria

Exclusion criteria: Patients after scheduled surgery, Platelet and coagulation disorders including antithombotic drug therapy, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, patients with inflammatory diseases, or chromosomal abnormalities.

Design outcomes

Primary

Measure	Time frame
To evaluate the differences in platelet messenger RNA and microRNA expression using next-generation sequencing, PCR, and other methods between patients with sepsis, distinguishing those with and without platelet reduction, and comparing these findings to non-sepsis patients.	—

Countries

Japan

Contacts

Public ContactYasufumi Nakajima

Kansai Medical University Department of Anesthesiology

nakajima@med.kindai.ac.jp0723660221

Outcome results