Coronary Plaque Characterization by Near-infrared Spectroscopy for Identification of Plaque Vulnerability: Association with Coronary Computed Tomographic Angiography

Coronary Plaque Characterization by Near-infrared Spectroscopy for Identification of Plaque Vulnerability: Association with Coronary Computed Tomographic Angiography - Coronary Plaque Characterization by NIRS: Association with CCTA

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000043115

Enrollment

200

Registered

2021-01-24

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Heart Disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. At least 18 years of age 2. De novo, native coronary artery lesions 3. Blood cardiac biomarker (Troponin-T) levels less than the local laboratory the upper limit of normal (ULN) before PCI 4. Both NIRS and OCT catheters use are not contra-indicated 5. The lesion received one stent during the initial procedure

Exclusion criteria

Exclusion criteria: 1. Prior coronary revascularization therapy (PCI and/or CABG) to target vessel 2. STEMI within the past 24 hours 3. Simultaneously treated with multi-vesssel PCI on initial procedure 4. LMT case 5. Chronic kidney disease (serum creatinine on admission more than 1.5 mg/dl) 6. Presented with hemodynamic instability (cardiogenic shock) 7. Complex lesion which need to do balloon dilatation (more than 2.0mm balloon or debulking device before pre-procedural NIRS-IVUS 8. Poor image quality case which the technician cannot perform either CTA or NIRS-IVUS measurements 9. Lesions with an EEM diameter <2.0mm

Design outcomes

Primary

Measure	Time frame
Relationship between lipid core burden index (LCBI) as detected by NIRS-IVUS, and plaque characteristics by CCTA in coronary lesions.	—

Countries

Japan

Contacts

Public ContactHideaki Ota

Gifu Heart Center Department of Cardiology

ota@heart-center.or.jp058-277-2277

Outcome results