Comparison of intrathecal midazolam and fentanyl added to bupivacaine for spinal anesthesia in patients undergoing appendicectomy

Comparison of intrathecal midazolam and fentanyl added to bupivacaine for spinal anesthesia in patients undergoing appendicectomy - Comparison of intrathecal midazolam and fentanyl added to bupivacaine for spinal anesthesia in patients undergoing appendicectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043105

Enrollment

Registered

2021-01-23

Start date

2018-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrathecal midazolam and fentanyl added to bupivacaine for spinal anesthesia in patients undergoing appendicectomy

Interventions

Group BM: Intrathecal 3ml of 0.5% hyperbaric Bupivacaine with 0.4ml (2mg) midazolam Group BF: Intrathecal 3ml 0.5% hyperbaric Bupivacaine with 0.4mls (20micrograms) Fentanyl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Scheduled for elective or emergency appendicectomy requiring sub arachnoid block. 2) All patients of ASA physical status I-II. 3) Age group of 15-70 yrs of age.

Exclusion criteria

Exclusion criteria: 1) Patient refusal. 2) Infection at the site of injection. 3) Deformities of spinal column. 4) Mental disturbance or neurological disease. 5) Known case of allergic to drugs used.

Design outcomes

Primary

Measure	Time frame
Intrathecal midazolam and fentanyl added to bupivacaine in patients undergoing appendicectomy reduces intraoperative pain and increases duration of post-operative analgesia.	—

Countries

Asia(except Japan)

Contacts

Public ContactPuja Thapa

Nepalese Army Institute of Health Sciences Bagmati

thapa_puza@yahoo.com+9779851152449

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026