An evaluation of the change of plasma carotenoid concentration after the co-ingestion of sterilized fermented milk and vegetables in human subjects.

An evaluation of the change of plasma carotenoid concentration after the co-ingestion of sterilized fermented milk and vegetables in human subjects. - An evaluation of the change of plasma carotenoid concentration after the co-ingestion of sterilized fermented milk and vegetables in human subjects.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000043010

Enrollment

Registered

2021-01-16

Start date

2021-02-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Subjects receive a single dose of the placebo food. After the washout period (13 days or more), subjects receive a single dose of the active food (low dose). After the washout period (13 days or more)

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) Subjects giving written informed consent 2) Males aged 20 to 35 years old when consent acquisition 3) Subjects whose body mass index (BMI) is from 18.5 kg/m2 to 25.0 kg/m2

Exclusion criteria

Exclusion criteria: 1) Subjects who routinely use pharmaceuticals, quasi-drugs, dietary supplement, and consume food for specified health uses, supplements containing carotenoids more than two days per week 2) Subjects who have chronic diseases necessitating treatments and/or medications 3) Subjects who have abnormal lipid metabolism, glucose metabolism, liver function, or kidney function 4) Subjects who have food allergy 5) Subjects who have lactose intolerance 6) Subjects who received digestive surgical procedures 7) Subjects who are habitual smokers within a month of study enrollment 8) Subjects who donate 200 mL of blood within a month, or 400 mL of blood within three month 9) Subjects who participate in other clinical trials within the past month or have plans to participate in other clinical trials during this study period 10) Subjects who determine ineligible by the principal investigator or sub-investigator

Design outcomes

Primary

Measure	Time frame
Plasma beta-carotene concentration (TRL fraction)	—

Secondary

Measure	Time frame
Plasma alpha-carotene, lycopene, lutein, zeaxanthin, beta-cryptoxanthin, total carotenoid and retinyl palmitate concentration (TRL fraction). Plasma beta-carotene, alpha-carotene, lycopene, lutein, zeaxanthin, beta-cryptoxanthin, total carotenoid and retinyl palmitate concentration (All fraction).	—

Countries

Japan

Contacts

Public ContactMasashi Morifuji

Meiji Co., Ltd Food Microbiology Research Laboratories, R&D Division

masashi.morifuji@meiji.com042-632-5838

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026