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The impact of reverse triggering on achieving low tidal volume for patients with respiratory failure

The impact of reverse triggering on achieving low tidal volume for patients with respiratory failure - The impact of reverse triggering on achieving low tidal volume for patients with respiratory failure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000042971
Enrollment
30
Registered
2021-01-11
Start date
2021-01-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute respiratory failure, ARDS

Interventions

Tidal volume 6 ml/kg (Predicted Body Weight) [Time frame: during 15 minutes] Tidal volume 7.5 ml/kg (Predicted Body Weight) [Time frame: during 15 minutes]

Sponsors

Hiroshima University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Age > 20 years old, <85 years old Acute respiratory failure and ARDS (PaO2/FIO2 < 300mmHg) Those who can obtain written consent from the substitute for participation in this study Receiving intubation within 72 hours Being expected to receive mechanical ventilation at least 72 hours.

Exclusion criteria

Exclusion criteria: Receiving neuromuscular blockage brain death bronchoalveolar fistula post esophageal cancer surgery contraindication to Edi catheter insertion (Esophageal varices and perforation) using ECMO (extracorporeal membrane oxygenation) mechanical ventilation due to asthma and COPD hemodynamic instability pregnant patient Those who are deemed inappropriate by the principal investigator or research co-investigator

Design outcomes

Primary

MeasureTime frame
Prevalence of reverse triggering [Time frame: during 45 minutes]—

Countries

Japan

Contacts

Public ContactTatsutoshi Shimatani

Hiroshima University Department of Emergency and Critical Care Medicine

tatsutoc@gmail.com082-257-5456

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026