N/A (healthy adults)
Conditions
Interventions
Intake the test food (Collagen-containing food) for 12 weeks
Intake the control food for 12 weeks
Sponsors
Akanuma Surgery Clinic Clinical Trials Division
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Japanese males and females between the ages of 20 and less than 75 at the time of obtaining consent to participate in the test 2)Healthy persons who are not currently being treated for any serious illness 3)Those who are not patients with OA (gonarthrosis) or rheumatism but have discomfort in the knees 4)Those with JKOM pain VAS of 20 mm or more (preferably 50 mm or less) 5)JKOM III those with a high score in daily living conditions (Q9-18) 6)Those who can visit the designated facility on the scheduled visit date 7)Those who fully understand the purpose and content of this test and have agreed in writing
Exclusion criteria
Exclusion criteria: 1)Patients with OA (gonarthrosis, grade II or higher in KL classification), RA and/or goat 2)Those who have difficulty to participate in this study because of conditions i.e., liver, kidney, or cardiac disease, breathing, endocrinology, metabolism, nervous, or conscious disorder, diabetes (determined by JDA), and other diseases 3)Those with history of cardiovascular diseases 4)Those who use medicines, health foods and supplements (including "Food for specified health uses", "Foods with function claims" and "Food with nutrient function claims") constantly, excepting those who can stop them at taking of informed consent 5)Those who have allergies related to test food (collagen) 6)Previous experience of poor or worsened health after giving a blood sample 7)Blood donations 200 mL or more in the month before the trial or have plans for making a blood donation 200 mL or more during the trial period 8)Participation in another clinical trial, whether ongoing or within the last four weeks 9)Heavy drinkers and smokers 10)Extremely irregular dietary patterns 11)Those with a BMI of 25.0 or higher at the time of pre-examination 12)Those with a walking speed of 1.6 m / sec or more when walking 10 m (maximum walking speed) 13)Those who do not wish to provide their consent to the details of the trial explained to them in advance 14)Those who judged that examination responsible doctor is not appropriate for this study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee passive range of motion measurement | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)JKOM 2)VAS of discomfort in the knee (when resting, walking, climbing stairs) 3)10m walking (normal speed, maximum speed, number of steps) 4)Stair climbing test | — |
Countries
Japan
Contacts
Public ContactMegumi Takahashi
Ryusendo Co., Ltd. Development Division
Outcome results
None listed