Hip osteoarthritis
Conditions
Interventions
Mirogabalin 15mg was given at 2 hours before surgery. From 24 hours after surgery, study group patients received mirogabalin (15mg twice per day) for 2 days.
On the day of surgery, postoperative pain
Sponsors
Nishinomiya Kaisei hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients recruited were of the American Society of Anesthesiologists (ASA) grade 1-3 rating, unilateral primary THA under general anesthesia, and the ability to cooperate with the investigation and understand the pain scale.
Exclusion criteria
Exclusion criteria: Exclusion criteria included patients with dementia or mental disorders, known drug allergy or tolerance to study drugs, renal insufficiency or abnormal liver enzymes, severe cardiovascular disease, severe diabetes, who have not been used the modified Watson-Jones approach, who have undergone bilateral simultaneous THA, and who have not passed more than 6 months from previous the other side THA.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome was total fentanyl consumption over the initial 24h postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| The postoperative numerical rating scale (NRS) at rest, the active, and passive NRS score during hip exercise. Chronic pain was evaluated using a chronic pain grading scale (CPGS) at 6 months after surgery. | — |
Countries
Japan
Contacts
Public ContactYu Takeda
Nishinomiya Kaisei hospital Department of Orthopaedics
Outcome results
None listed