Healthy adults
Conditions
Interventions
Ultraviolet of 222 nm at 22 mJ / cm2 are irradiated.
Ultraviolet of 222 nm at 50 mJ / cm2 are irradiated.
Ultraviolet of 222 nm at 50 mJ / cm2 are irradiated.
Ultraviolet of 222 nm at 75 mJ / cm2 are
Sponsors
Shimane University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Those who obtained document consent by their own voluntary intention about participation in this trial 2)Avoiding exposure for ultraviolet within 48 hours. 3)Corrected visual acuity 0.04 4)Not being treated for eye diseases that affect eyesight. .5)Do not use eye drops or topical medication for facial skin
Exclusion criteria
Exclusion criteria: 1)People wearing contact lens. 2)Engaged in out door work that are exposed UV(field work, welding, etc.). 3)Anyone with abnormalities in the cornea.(corneal eroion D score > 2, or congestion score >2.) 4)Patient with dryeye. 5)Patient with atopic dermatitis. 6)Patient with sun sensitivity. 7)Participating in clinical trials involving other interventions or will participate between the enrollment of this study and the end of observation. 8)Others who are judged inappropriate by the doctor in charge of this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of Corneal erosion and conjunctival hypermia at 24 hour,1 month, 3 months and 6 months after ultraviolet irradiation | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity, refractive power, corneal cell density, skin erythema, adverse events | — |
Countries
Japan
Contacts
Public ContactKazunobu Sugihara
Shimane University Ophthalmology
Outcome results
None listed