food allergy
Conditions
Interventions
Patients suspected of peanut allergy receive stepwise oral food challenge. Patients with Ara h 2 specific IgE greater than 4.0 kUA/L start with a very low dose oral food challenge. Patients with Ara
oral food challenge with 0.12g of peanut powder Low dose oral food challenge
oral food challenge with 0.5g of peanut or peanut powder contained in foods such as pumpkin cake and hamburger steak Middle dose oral food challenge
oral food challenge with 3g of peanut or peanut powder contained in foods such as pumpkin cake and hamburger steak Full dose oral food challenge
oral food challenge with 10g of peanut or peanut powder contained in foods such as pumpkin cake and hamburger steak The patients who pass each oral food challenge receive next oral food challenge i
2 times at home. The patients classified as negative or uncertain in low dose or middle dose or full dose oral food challenge are instructed to consume the same amount >
2 times at home.
Sponsors
National Hospital Organization Sagamihara National Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who receive peanut oral food challenges at our hospital
Exclusion criteria
Exclusion criteria: The subjects who are undergoing oral immunotherapy or epicutaneous immunotherapy The subjects who disagree to participate in the study The subjects judged inappropriate for the study by the research director
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of positive oral food challenge The rate of anaphylaxis induced by oral food challenge | — |
Secondary
| Measure | Time frame |
|---|---|
| Reproducibility of negative or uncertain oral food challenge results at home The change in peanut, Ara h 2 specific IgE levels | — |
Countries
Japan
Contacts
Public ContactKen-ichi Nagakura
National Hospital Organization Sagamihara National Hospital Department of Pediatrics
Outcome results
None listed