Healthy female adults
Conditions
Interventions
Infusion of the test apparatus-generated hydrogen into the subject'
s eyelids with the close eye for 5 min.
Infusion of the air equivalent to the above-mentioned hydrogen into the subject'
s eyelids with the close eye for 5 min.
Sponsors
CPCC Company Limited
Graduate School of Integrative and Global Majors, Tsukuba University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Healthy female subjects ranging in age from 20 to 39, at the moment of giving informed consent to take part in this trial. (2) Subjects equipped with asthenopia and daily stress. (3) Subjects who can give informed consent to participate in this research after being provided with an explanation of the protocol detail.
Exclusion criteria
Exclusion criteria: (1) Subjects falling into the habit of smoking. (2) Subjects with the condition of being over-sensitiveness to cold, even during the summer season. (3) Subjects taking steadily in the medicine and/or the health-specific/functional/health foods, which might affect their blood flow improvement. (4) Subjects with some kind of eye disease in and around their eyes/eyelids. (5) Pregnant, possibly pregnant, or lactating women. (6) Subjects having previous/present medical history of serious diseases in heart, liver, kidney, and/or digestive organs. (7) Subjects with some kind of skin symptom, disease or disorder, just like atopic dermatitis. (8) Subjects who have undergone some kind of surgical treatment for the measurement region, within the last six months into this trial. (9) Subjects with high blood pressure-- a maximal blood pressure of not less than 160 mmHg, a minimal blood one of not less than 100 mmHg--, and so on. (10) Subjects who realized that the subjects themselves must be in a state of menopausal disorder. (11) Subjects who are now under the other clinical tests with some kind of medicine/food, or took part in those within four weeks before this trial, or are planning to participate in those after giving informed consent to take part in this trial. (12) Others who have been determined as ineligible for participation, judging from the investigator's opinions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Facial blood flow 2. Dynamic visual acuity 3. Flicker 4. Mental age | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Oxytocin in saliva 2. Multiple measurements of emotion using a multiple mood scale (short ver.) 3. Brain waves (2 ch) | — |
Countries
Japan
Contacts
Public ContactMasanori Numa
CPCC Company Limited Clinical Planning Department
Outcome results
None listed